Uterine Cancers

NewYork-Presbyterian offers the full suite of services for uterine cancers. Our teams have expertise treating endometrial cancer—cancer of the uterine lining, the most common type—as well as uterine sarcomas (less common tumors which arise in the uterine wall). We have special expertise treating leiomyosarcoma, carcinosarcoma, and malignant mixed Mullerian tumors of the uterus and offer clinical trials of promising new therapies to women with these rare cancers. If you are in your childbearing years and interested in having children, we try to preserve your fertility whenever that is an option.

A Team of Uterine Cancer Specialists

We will assemble the team of uterine cancer experts best suited to your care. Our teams include gynecologic oncologists, pathologists, radiologists, nurses, and others with the skills and compassion to treat women with uterine cancers. Together they will tailor a plan of treatment that meets your specific needs.

Minimally Invasive Surgery

Hysterectomy—surgery to remove the uterus, and sometimes the fallopian tubes and ovaries—is the most common treatment for uterine cancers. Our surgeons often perform this procedure using robotic and laparoscopic surgeries, minimally invasive approaches associated with smaller incisions, less postoperative discomfort, and a quicker return to your normal activities. If you are interested in having children in the future, your surgeon will discuss your options with you to see if your surgery can preserve your fertility. Your surgeon will also remove lymph nodes in your pelvis to see if they contain cancer cells; this process, called staging, will determine if you need treatment other than surgery and is a specialty of NewYork-Presbyterian's gynecologic oncologists.

Radiation Therapy and Chemotherapy

Some women with uterine cancers, especially sarcomas, may need radiation therapy or chemotherapy in addition to surgery if cancer cells may have spread beyond the uterus. You can receive finely targeted radiation therapy in our state-of-the-art radiation treatment centers, and chemotherapy in our modern and comfortable infusion centers. These centers are staffed by professionals whose goal is to cure your cancer while supporting your health and well-being.

  • Presurgical radiation. In a very few number of cases, women with uterine sarcomas receive radiation therapy before surgery, to shrink the tumor.
  • Brachytherapy. In some cases, radiation therapy is applied directly to the tumor in the operating room. Known as brachytherapy, NewYork-Presbyterian offers this procedure when deemed medically necessary.
  • Hormonal therapy. Some women with uterine cancer receive hormonal therapy to inhibit tumor growth. Your doctors will let you know the best course of care for you.
  • Targeted therapies. Molecular targeted therapies can sometimes be utilized for uterine cancers. Your doctor may obtain molecular testing n your tumor that can help identify specific genetic abnormalities that can be targeted with specific drugs that are clinically available or available as part of a clinical trial. This approach to cancer therapy is called precision medicine.

Treating All of You

We understand how a diagnosis of cancer can affect your life and the lives of your loved ones. Your team includes other healthcare professionals you may need for the treatment of symptoms, as well as psychosocial support, rehabilitation, and nutrition during and after cancer therapy.

Clinical Trials

Our gynecologic cancer specialists participate in and lead clinical trials assessing promising new treatments for gynecologic cancers. Your doctor will let you know if you are eligible to participate in a clinical trial of an innovative therapy for uterine cancer. Learn More.