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Profile - Dr. Sharon E. Oberfiel
Sharon E. Oberfield, <span>MD</span>

Sharon E. Oberfield, MD

Pediatric Endocrinology (Board Certified, Primary Specialty)
Pediatrics (Board Certified)
Office Phone: (212) 305-6559
One of America's Top Doctors
Rated one of New York Magazine's Best Doctors

Biography

Dr. Oberfield is a Professor of Pediatrics and since 2004 has been the Director of the Division of Pediatric Endocrinology, Diabetes, and Metabolism at Columbia University Medical Center. She also was the Program Director for the Fellowship Training program in Pediatric Endocrinology and is currently the Associate Program Director. She is the PI of a T32 training grant in Pediatric Endocrinology from the NIH National Institute of Diabetes, Digestive, and Kidney Diseases since 2005. She has been engaged in patient-oriented research for her entire career with a particular focus on disorders of adrenal hormone synthesis, adrenarche, and PCOS. She has conducted studies of body composition in children and continues to be involved in multiple studies of childhood obesity.

Since 1998, she has mentored more than 25 fellows and more than 30 pre-doctoral students including Endocrine Society, DERC, and Doris Duke summer fellows. Her clinical research has centered around the developmental/pediatric endocrinology, specifically the HPA axis which intimately affects metabolic function, interacting with adiposity, including studies of body composition in adrenarche and PCOS. She has been the author or co-author of more than 225 articles, multiple chapters and reviews, and is an invited speaker at national and international meetings, including the 2012 NIH-sponsored Evidence Based Methodology Workshop on Polycystic Ovary Syndrome. She is currently an editor for the Journal of Pediatrics and is an Associate Editor for Hormone Research in Pediatrics. She continues to be listed in Castle Connelly’s “America’s Top Doctors” and NY Magazine’s “Best Doctors."

Area of Expertise

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Education

Cornell University Medical College, NY

Internship: New York Hospital-Cornell Medical Center

Residency: New York Hospital-Cornell Medical Center

Fellowship: New York Hospital-Cornell Medical Center

Publications

Of more than 225 publications:

Mitchell JA, Chesi A, Cousminer DL, McCormack SE, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SFA. Multi-dimensional bone density phenotyping reveals new insights into genetic regulation of the pediatric skeleton. J Bone Miner Res, May 2018; 33(5):812-821. PMID: 29240982.

Ibanez L, Oberfield SE, Witchel S, Auchus RJ, Chang RJ, Codner E, Dabadghao P, Darendeliler F, Elbarbary NS, Gambineri A, Garcia Rudaz C, Hoeger KM, Lopez-Bermejo A, Ong K, Pena AS, Reinehr T, Santoro N, Tena-Sempere M, Tao R, Yildiz BO, Alkhayyat H, Deeb A, Joel D, Orikawa R, de Zegher F, Lee PA. An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence. Horm Res Paediatr, 2017 Nov;88(6):371-395. PMID: 29156452.

Widen EM, Whyatt RM, Hoepner LA, Mueller NT, Ramirez-Carvey J, Oberfield SE, Hassoun A, Perera FP, Gallagher D, Rundle AG. Gestational weight gain and obesity, adiposity and body size in African-American and Dominican children in the Bronx and Northern Manhattan. Matern Child Nutr. 2016 Oct;12(4):918-28. PMID: 25753294.

Maresca MM, Hoepner LA, Hassoun A, Oberfield SE, Ramirez JE, Freyer GA, Perera FP, Whyatt RM, and Rundle AG. Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort. Environ Health Perspect. 2016 April;124(4):514-20. PMID: 26069025.

Mitchell JA, Chesi A, Elci O, McCormack SE, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SF, Zemel BS. Genetic risk scores implicated in adult bone fragility associate with pediatric bone density. J Bone Miner Res. 2016 April;31(4):789-95. PMID: 26572781.

Mueller NT, Whyatt R, Hoepner L, Oberfield S, Dominguez-Bello MG, et al. Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity. Int J Obes (Lond). 2014 Nov 11;PubMed PMID: 25298276.

Kelly A, Winer KK, Kalkwarf H, Oberfield SE, Lappe J, et al. Age-based reference ranges for annual height velocity in US children. J Clin Endocrinol Metab. 2014 Jun;99(6):2104-12. PubMed PMID: 24601728; PubMed Central PMCID: PMC4037731.

Rundle A, Hoepner L, Hassoun A, Oberfield S, Freyer G, et al. Association of childhood obesity with maternal exposure to ambient air polycyclic aromatic hydrocarbons during pregnancy. Am J Epidemiol. 2012 Jun 1;175(11):1163-72. PubMed PMID: 22505764; PubMed Central PMCID: PMC3491973.

Kalkwarf HJ, Zemel BS, Gilsanz Z. Oberfield S, et al. The bone mineral density in childhood study: bone mineral content and density according to age, sex, and race. J Clin Endocrinol Metab. 2007 Jun;92(6):2087-99. PubMed PMID: 17311856.

Oberfield SE. Childhood cancer cures: the ongoing consequences of successful treatments. J Pediatr. 2007 Apr;150(4):332-4. PubMed PMID: 17382105.

Silfen ME, Manibo AM, Ferin M, McMahon DJ, Levine LS, Oberfield SE. Elevated free IGF-I levels in prepubertal Hispanic girls with premature adrenarche: relationship with hyperandrogenism and insulin sensitivity. J Clin Endocrinol Metab. 2002 Jan;87(1):398-403. PubMed PMID: 11788683.

Sopher AB, Thorton JC, Silfen ME, Manibo A, Oberfield SE, et al. Prepubertal girls with premature adrenarche have greater bone mineral content and density than controls. J Clin Endocrinol Metab. 2001 Nov;86(11):5269-72. PubMed PMID: 11701690.

Silfen ME, Manibo AM, McMahon DJ, Levine LS, Murphy AR, Oberfield SE. Comparison of simple measures of insulin sensitivity in young girls with premature adrenarche: the fasting glucose to insulin ratio may be a simple and useful measure. J Clin Endocrinol Metab. 2001 Jun;86(6):2863-8. PubMed PMID: 11397901.

Oberfield SE, Nirenberg A, Allen JC, Cohen H, Donahue B, et al. Hypothalamic-pituitary-adrenal function following cranial irradiation. Horm Res. 1997;47(1):9-16. PubMed PMID: 9010712.

Oberfield SE, Nino M, Riddick L, Pang S, Nagel M, et al. Combined bromocriptine and growth hormone (GH) treatment in GH-deficient children with macroprolactinoma in situ. J Clin Endocrinol Metab. 1992 Jul;75(1):87-90. PubMed PMID: 1619034.

Oberfield SE, Mayes DM, Levine LS. Adrenal steroidogenic function in a black and Hispanic population with precocious pubarche. J Clin Endocrinol Metab. 1990 Jan;70(1):76-82. PubMed PMID: 2152934.

Oberfield SE, Allen JC, Pollack J, New MI, Levine LS. Long-term endocrine sequelae after treatment of medulloblastoma: prospective study of growth and thyroid function. J Pediatr. 1986 Feb;108(2):219-23. PubMed PMID: 3944706.

Oberfield SE, Levine LS, Carey RM, Greig F, Ulick S, et al. Metabolic and blood pressure responses to hydrocortisone in the syndrome of apparent mineralocorticoid excess. J Clin Endocrinol Metab. 1983 Feb;56(2):332-9. PubMed PMID: 6296185.

Oberfield SE, Levine LS, Stoner E, Chow D, Rauh W, et al. Adrenal glomerulosa function in patients with dexamethasone-suppressible hyperaldosteronism. J Clin Endocrinol Metab. 1981 Jul;53(1):158-64. PubMed PMID: 7016891.

Oberfield SE, Levine LS, Carey RM, Bejar R, New MI. Pseudohypoaldosteronism: multiple target organ unresponsiveness to mineralocorticoid hormones. J Clin Endocrinol Metab. 1979 Feb;48(2):228-34. PubMed PMID: 218983.