Orthopedic Oncology (Bone Tumors)

Physicians at Weill Cornell Orthopedics at NewYork-Presbyterian/Weill Cornell Medical Center offer a comprehensive program to diagnose and treat primary and metastatic bone tumors.

Conditions We Treat

  • Bone tumors
  • Soft tissue tumors
  • Soft tissue sarcomas*
  • Blood cancers*

(*In collaboration with Hospital oncologists)


To determine if a bone or soft tissue tumor is present, our physicians often collaborate with the hospital's radiologists to administer and interpret imaging tests such as PET scans, CT scans, and MRIs. We may also perform a fine needle biopsy, where a small sample of bone or tissue is removed and analyzed to determine if cancer is present. In addition, we may use a test called flow cytometry, which allows physicians to examine the DNA in cells and determine if cancer is present.


We offer a range of treatments for bone and soft tissue tumors. They are often combined with chemotherapy before surgery to shrink a tumor, or after surgery to destroy any remaining cancer cells. Examples of our therapies include:

Cryotherapy Ablation

During cryotherapy ablation, surgeons insert several needles into the tumor site to freeze and destroy cancer cells. Argon and helium gas circulate through the needles, lowering the temperature to -40°C for several minutes.

Radiofrequency Ablation

With this procedure, a probe that emits a high radio frequency is guided to the tumor site. The radio frequency creates an intense heat that destroys the tumor.

Limb Salvage Surgery

With this therapy, the tumor is surgically removed and the limb is reconstructed with modified joint replacement, allografts, or a combination of these approaches.

Bisphosphonate Drug Therapy

After a bone tumor is destroyed, a type of drug known as a bisphosphonate may be given to patients, by mouth (orally) or by vein (intravenously). This therapy helps strengthen bones which have been weakened by tumors. (It is also the same type of drug given to patients whose bones are weakened by osteoporosis). Bisphosphonate drug therapy may be used with PMMA bone cement, a medical grade cement that doctors use to surgically fill a void within a bone after a tumor is destroyed. PMMA cement helps strengthen the bone and prevent the tumor from coming back.

Amputation and Prosthetics

For patients with advanced cancer whose limbs cannot be salvaged, we may perform amputation, coupled with state-of-the-art prosthetics and rehabilitation to help patients achieve a high level of performance.


Weill Cornell Orthopedics was the first group in the United States to investigate the direct insertion of prosthetics into bone without the need of a socket for amputees.

Our Physicians for Orthopedic Oncology (Bone Tumors)


HSS at NewYork-Presbyterian Weill Cornell Medicine

NewYork-Presbyterian/Weill Cornell Medical Center
Phone: 212-746-4500