Clinical Trials

NewYork-Presbyterian is heavily involved in research on amyloidosis. The Program's leader, Suzanne Lentzsch, M.D., Ph.D., is the principal investigator of a multicenter trial in the Amyloidosis Network which includes five leading centers in the United States. The researchers are studying the pathomechanism of systemic amyloidosis and ways to improve patient care. Preliminary results are very promising and enrollment is currently open. In addition, there are a number of other amyloidosis-related clinical trials currently being conducted by Program researchers. During the amyloidosis multidisciplinary meetings, specialists spend time discussing clinical trials and new ideas in research. Patients who are treated for amyloidosis at NewYork-Presbyterian may be able to take part in clinical trials of emerging therapies.

Clinical Trials

Below is a listing of clinical trials for Amyloidosis currently taking place at NewYork-Presbyterian.

  1. Study of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL Amyloidosis. At NCT02245867
  2. APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis. At NCT01960348
  3. Bendamustine and Dexamethasone in Patients With Relapsed AL Amyloidosis. At NCT01222260
  4. A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis. At NCT01789242
  5. Study of Dexamethasone Plus IXAZOMIB or Physician's Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis. At NCT01659658
  6. Efficacy and Safety of ISIS-TTR Rx in Familial Amyloid Polyneuropathy. At NCT01737398
  7. Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy. At NCT00935012
  8. Transthyretin-Associated Amyloidoses Outcome Survey (THAOS). At NCT00628745
  9. Local studies taking place only at NewYork-Presbyterian and not listed on



Myeloma Center
NewYork-Presbyterian/ Weill Cornell


Multiple Myeloma and Amyloidosis Service
NewYork-Presbyterian/ Columbia


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