How Is Colitis Diagnosed?

How Is Colitis Diagnosed?

If you are experiencing symptoms indicating potential colon inflammation, your doctor can perform a series of tests to confirm a colitis diagnosis.

Lab tests

  • Blood tests can show signs of infection, inflammation, or anemia – a condition in which the blood lacks the requisite red blood cells to carry oxygen throughout the body.
  • Stool studies can reveal white blood cells or certain proteins which indicate ulcerative colitis. Stool studies can also help rule out other diseases.

Endoscopic procedures

  • Colonoscopy is an exam in which a thin, flexible, lighted tube with a camera is inserted through the rectum to allow your doctor to view the entire colon. Tissue samples may be taken and biopsied during a colonoscopy to confirm a diagnosis. This is typically done while the patient is sedated as a same-day procedure.
  • Flexible sigmoidoscopy is a procedure where a thin, lighted tube is used to examine the rectum and sigmoid colon — the lower end of your colon. This procedure may be performed in the office without sedation.

Imaging procedures

  • X-ray. In severe cases, an X-ray of the abdomen may be used to rule out serious complications, such as toxic megacolon or a perforated colon.
  • CT scan. If such complications are suspected, a Computerized Tomography (CT) scan of your abdomen/pelvis may be used as well. A CT scan may also be used to reveal the extent of inflammation.
  • CT enterography and magnetic resonance (MR) enterography are noninvasive, more sensitive imaging tests used to help rule out inflammation of the intestine.

How Is Colitis Treated?

How Is Colitis Treated?

Treatment for colitis depends on the type and severity of your condition. Some types of colitis can be managed with dietary changes, and many types of colitis can be controlled with a range of medications.

For more severe cases or those not managed with medicine, surgical options for colitis treatment are available.

Dietary changes

Making changes to your diet can go a long way toward reducing inflammation and preventing flare-ups if you have a chronic colitis condition. Eating smaller meals more often, staying hydrated, and drinking without a straw (which causes you to ingest air, causing gas) can reduce your symptoms. Dieticians available at NewYork-Presbyterian can create a customized regimen to improve mild symptoms without medications or surgery.

You can also avoid foods known to trigger abdominal pain and other symptoms of colitis, such as insoluble fiber foods (including raw green vegetables, fruits with skin, and whole grains), lactose, caffeine, alcohol, and foods high in sugar and fat content. Replace these foods with low-fiber fruits (like bananas and melon), lean proteins, fully cooked vegetables, and dietary supplements to round out your nutritional needs.

Medication

  • Anti-inflammatory medications are typically the first method used to control symptoms since colitis is a result of inflammation. These include 5-aminosalicylates, such as sulfasalazine and mesalamine, and corticosteroids, such as prednisone and budesonide, which are often used for more severe cases that don’t respond to other treatments.
  • Immunosuppressants reduce swelling by suppressing the immune system, which initiates the process of inflammation. These include azathioprine and mercaptopurine, typically used to treat inflammatory bowel diseases.
  • Biologics target proteins the immune system creates and are typically used to treat ulcerative colitis. The first medication used to treat inflammatory bowel disease (IBD) was tumor necrosis factor (TNF) inhibitors, which neutralize a protein naturally created by the immune system as part of an inflammatory response. Since then, many biologic medications have been created to target different pathways of the immune response.

Your doctor may also recommend over-the-counter medications such as anti-diarrheal medicines (like Imodium) and pain relievers (like Tylenol), or prescription-strength antispasmodic medications to be used during flare-ups.

Surgical options

For cases of ulcerative colitis that are not responsive to medications or dietary changes, your doctor may recommend a proctocolectomy, the process of surgically removing your entire colon and rectum. This procedure typically involves the construction of a pouch at the end of your small intestine, which is then attached to the anus, allowing for normal waste excretion.

This is commonly referred to as a “J-pouch” because the bowel resembles a “J” to function as a reservoir for stool before defecation to mimic the rectum before being surgically removed.

FAQs

FAQs

It is widely believed that ulcerative colitis and Crohn’s disease are autoimmune diseases (one in which the immune system is activated to respond and mistakenly attacks healthy cells). The immune system typically responds to infections by sending white blood cells into the blood, resulting in inflammation in the affected area.

Colitis caused by a temporary infection may dissipate on its own after a short time, particularly if you can alter your dietary intake to avoid foods that will worsen inflammation. More severe infections and conditions such as Crohn’s disease cause inflammation that must be addressed with medical treatment. Patients may have remission induced by medical or surgical therapy, or in some cases, it may happen spontaneously.

Acute cases of temporary colitis typically last about a week, though some infections can cause inflammation that takes several weeks or months to settle down.

It is generally believed that chronic conditions such as ulcerative colitis and Crohn’s disease are hereditary, with genetics being a leading risk factor.

Outside of a chronic condition, colitis is generally caused by a viral or bacterial infection, food poisoning, or radiation exposure.

Colitis is primarily characterized by abdominal pain that doesn’t go away, accompanied by diarrhea, fever, bloody stools, and loss of appetite.

If untreated, colitis can lead to extremely dangerous complications, including perforations in the colon, toxic megacolon, and an increased risk of colon cancer, which can be fatal.

Get Care

Trust NewYork-Presbyterian for Colitis Treatment

If you are concerned that you may have colitis, our experienced specialists at NewYork-Presbyterian can determine the cause and ensure you get the treatment and compassionate care you need. Call today to make an appointment at a location near you.