Research

Youth Anxiety Center - Research banner

The research mission of the Youth Anxiety Center is to advance our understanding of what causes anxiety, obsessive compulsive disorder (OCD), and related disorders, and to use that knowledge to develop better treatments for individuals and better services for communities. To accomplish this mission, researchers from Weill Cornell Medicine and Columbia University College of Physicians and Surgeons collaborate to determine the underlying causes of anxiety at the level of the brain in both animal and human studies, to develop and test innovative treatments that target these brain mechanisms in clinical trials, and to determine how to deliver effective treatments to the community

New research shows that changes in neural circuitry during adolescence may make it possible to easily diminish fear memories and avoid anxiety later in life. These findings have important implications for improving treatment of anxiety disorders.

Dynamic Changes in Neural Circuitry During Adolescence are Associated with Persistent Attenuation of Fear Memories. Pattwell SS, Liston C, Deqiang J, Ninan I, Yang, RR, Witztum J, Murdock MH, Dincheva, Kevin BG, Casey BJ, Deisseroth K & Lee FS. Nature Communications. May 2016.