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Orthopedic Oncology

Orthopedic Oncology (Bone Tumors)

Physicians at Weill Cornell Orthopedics offer a comprehensive program to diagnose and treat primary and metastatic types of cancer.

Our Physicians for Orthopedic Oncology (Bone Tumors)

Conditions we treat include:

  • Bone tumors
  • Soft tissue tumors
  • Soft tissue sarcomas *
  • Blood cancers *

(*In collaboration with Hospital oncologists)


To determine if a bone or soft tissue tumor is present, our physicians often collaborate with the Hospital's radiologists to administer and interpret imaging tests such as PET scans, CT scans, and MRIs. We may also take a fine needle biopsy where a small sample of bone or tissue is extracted and analyzed to determine if cancer is present.

Additionally, we may also use a test known as flow cytometry. This test allows physicians to examine the DNA in cells and determine if cancer is present. In addition to bone and soft tissue tumors, this test is also used to diagnosis blood cancers (leukemia, lymphoma, and myeloma).


We offer a range of treatments for bone and soft tissue tumors including cryotherapy ablation, radiofrequency ablation, and bisphosphonate drug therapy with PMMA bone cement. These treatments are often coupled with chemotherapy before surgery to shrink a tumor, or after surgery to destroy any remaining cancer cells.

Cryotherapy Ablation

During cryotherapy ablation, surgeons insert several needles into the tumor site to freeze and destroy the cancer cells. Argon and helium gas circulate through the needles, lowering the temperature to -40°C for several minutes.

Radiofrequency Ablation

Radiofrequency ablation uses high temperatures, not cold, to destroy the tumor. With the procedure, a probe that emits a high radio frequency is guided to the tumor site. The radio frequency creates an intense heat that destroys the tumor.

Limb Salvage Surgery

Removal of tumor and reconstruction of the limb with modified joint replacement, allografts or combination.

Bisphosphonate Drug Therapy

After a bone tumor is destroyed, a type of drug known as Bisphosphonate drug therapy may be given to patients, orally or intravenously. This therapy helps strengthened bones weakened by tumors. (It is also the same type of drug given to patients whose bones are weakened by osteoporosis). Bisphosphonate drug therapy may be used with PMMA bone cement, a medical grade cement that doctors use to surgically fill a void within a bone after a tumor is destroyed. PMMA helps strengthen the bone and prevent the tumor from recurring.

Amputation and Prosthetics

For patients with advanced cancer and whose limbs cannot be salvaged, we may perform amputations. These procedures are coupled with the introduction of state-of-the-art prosthetics and rehabilitation programs to give patients a continued high level of performance.


Weill Cornell Orthopedics is the first group in the United States to investigate the direct insertion of prosthetics into bone without the need of a socket for amputees.


Orthopedic Surgery, NewYork-Presbyterian/Weill Cornell
(212) 746-4500
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