Stanley Chang, MD

Ophthalmology
Office Phone: (212) 305-9535
One of America's Top Doctors
Rated one of New York Magazine's Best Doctors

Biography

Stanley Chang, M.D., is the former Edward S. Harkness Professor and Chairman of the Department of Ophthalmology at Columbia University Medical Center. He is also the K.K. Tse and Ku Teh Ying Professor of Ophthalmology. He is a specialist in vitreoretinal disorders and surgery and pioneered many of the surgical techniques currently used in this field.

Dr. Chang received a baccalaureate degree from the Massachusetts Institute of Technology, a Masters degree from the University of Pennsylvania, and completed his medical education at the College of Physicians and Surgeons of Columbia University. After fellowship, Dr. Chang joined the faculty of Department of Ophthalmology at Cornell University Medical School, where he became Professor of Ophthalmology. Appointed the Edward S. Harkness Professor and Chairman of the Department of Ophthalmology in 1995, he served as director of the Edward S. Harkness Eye Institute until 2012.

Dr. Chang has developed and pioneered several revolutionary surgical approaches to treat complicated forms of retinal detachment, improving outcomes for patients worldwide. He was the first to use perfluoropropane gas in the management of retinal detachments caused by scar tissue proliferation (PVR) on the retina. This gas is the most frequently used gas in vitreoretinal surgery. He developed perfluorocarbon liquids, a ‘heavy liquid’ used in flattening retinal detachment, and the related surgical techniques for vitreoretinal surgery. In collaboration with Avi Grinblat, he developed a panoramic viewing system and led in the worldwide adaptation by retina surgeons to this technique. In leading a world class Department and vision research institute, he continues to improve the clinical outcomes for patients through research and innovation. He is the recipient of several honors including the Hermann Wacker Prize from the Club Jules Gonin, Helmerich Prize from the American Society of Retinal Specialists, the Lifetime Achievement Award and the Secretariat Award from the American Academy of Ophthalmology, the Jackson Lecture and the Alcon Research Institute Award. Consistently named as one of America’s best doctors, Dr. Chang was recently recognized as one of three physicians selected as National Physician of the Year by the Castle Connolly Guides (2008).

The Department of Ophthalmology is grateful to Dr. Chang for his exemplary and inspirational leadership during his time as Chair and Director of Ophthalmology. During his tenure, the department attracted a top-notch team of researchers and clinicians, developed new faculty practices in New York and New Jersey, more than doubled the number of surgical cases in the Eye Institute, and dramatically increased research funding. Dr. Chang remains an active member of the faculty and continues his patient care, research and teaching commitments.

Area of Expertise

Medicare [Medicare]

Oxford Health Plans [Medicare]

UnitedHealthcare [HMO, Medicare, POS, PPO]

Education

Columbia University College of Physicians and Surgeons

Internship: Columbia Presbyterian Medical Center

Residency: Massachussetts Eye & Ear Infirmary

Fellowship: Bascom Palmer Eye Institute

Publications

Original Articles:

Chang S. Controversies regarding internal limiting membrane peeling in idiopathic epiretinal membrane and macular hole. Retina 2012 Sep;32 Suppl 2:S200-4.

Johnson MW, Brucker AJ, Chang S, Gandorfer A, Kampik A, Kuppermann BD, Russell SR, Spaide RF, Thompson JT. VITREOMACULAR DISORDERS: Pathogenesis and treatment. Retina 2012 Sep; 32 Suppl 2:S173.

Gregory-Roberts E, Mateo C, Corcostegui B, Schiff WM, Chang LK, Quiroz-Mercado H, Park S, Chang S. Optic disk pit morphology and retinal detachment: optical coherence tomography with intraoperative correlation. Retina 2012 (in press)

Stalmans P, Benz MS, Gandorfer A, Kampik A, Girach A, Pakola S, Haller JA; MIVI-TRUST Study Group. Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes. N Engl J Med 2012;367:606-15.

Santos RA, Keegan DJ, Fuchs BS, Song BJ, Avila MP, Simpson N, Sparrow J, Chang S. DFPE, PARTIALLY FLOURINATED ETHER: A novel approach for experimental intravitreal tamponade. Retina 2012;July 16 [Epub ahead of print].

Chang S, Gregory-Roberts E, Chen R. Retinal Detachment associated with optic disc colobomas and morning glory syndrome. Eye (Lond) 2012;26:494-500. Epub 2012 Jan 13.

Park SP, Chang S, Allikmets R, Smith TR, Burke TR, Gregory-Roberts E, Tsang SH. Disruption in Bruchs membrane in patients with Stargardt disease. Ophthalmic Genet 2012;33:49-52. Epub 2011 Nov 7.

Burke TR, Rhee DW, Smith TR, Tsang SH, Allikmets R, Chang S, Lazow MA, Hood DC, Greenstein VC. Quantification of peripapillary sparing and macular involvement in Stargardt disease (STGD1). Invest Ophthalmol Vis Sci 2011;52:8006-15.

Koreen L, Yoshida N, Esacariao P, Niziol LM, Koreen IV, Musch DC, Chang S. Incidence of, risk factors for, and combined mechanism of late-onset open-angle glaucoma after vitrectomy. Retina 2012;32:160-7.

Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J, Lowenstein A, Yoon YH, Jiao J, Li XY, Whipcup SM; Ozurdex GENEVA Study Group. Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion twelve-month study results. Ophthalmology 2011;118:2453-60. Epub 2011 July 20.

Chang S, Smith SD. Comment Re: Yu AL, Brummeisl W, Schaumberger M, Kampik A, Welge-Lussen U (2010) Vitrectomy does not increase the risk of open-angle glaucoma or ocular hypertension – a 5 year follow-up. Graefes Arch Clin Exp Ophthalmol 248:1407-1414. Graefes Arch Clin Exp Ophthalmol 2012;461-2. Epub 2011 Apr 8.

Hwang JC, Del Priore LV, Freund KB, Chang S, Iranmanesh R. Development of subretinal fibrosis after anti-VEGF treatment in neovascular age-related macular degeneration. Opthalmic Surg Lasers Imaging. 2011;42:6-11. Epub 2010 Sep 29.

Fine HF, Iranmanesh R, Del Priore LV, Barile GR, Chang LK, Chang S, Schiff WM. Surgical outcomes after massive subretinal hemorrhage secondary to age-related macular degeneration. Retina. 2010;30:1588-94.

Hwang JC, Gelman SK, Fine HF, Chang S, Del Priore LV. Combined arteriovenous sheathotomy and intraoperative intravitreal triamcinolone acetonide for branch retinal vein occlusion. Br J Opthalmol. 2010;94:483-9. Epub 2010 Sep 9.

Braunstein A, Trief D, Wang NK, Chang S, Tsang SH. Vitamin A deficiency in New York City. Lancet. 2010;376(9737):267.

Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J, Lowenstein A, Yoon YH, Jacques ML, Jiao J, Li XY, Whitcup SM; Ozurdex GENEVA Study Group. Ophthalmology 2010;117:1134-1146. Epub 2010 Apr 24.

Haller JA, Kuppermann BD,Blumenkranz MS,Williams GA, Weinberg DV, Chou C, WhipcupSM; Dexamethsone DDS Phase II Study Group. Arch Ophthalmol 2010;128:289-96.

Fine HF, Cunningham ET, Kim E, Theodore Smith R, ChangS. Autofluorescence imaging findings in long-standing chorioretinal folds. Retin Cases Brief Rep. 2009 3: 137-139.

Kuppermann BD, Chou C, Weinberg DV, Whitcup SM, Haller JA, Blumenkranz MS, Dexamethasone DDS Phase II Study Group. Intravenous dexamethasone effects on different patterns of diabetic macular edema. Arch Ophthalmol 2010;128:642-3. E pub 2010 Mar 8.

Wang NK, Fine HF, Chang S, Chou CL, Cella W, Tosi J, Lin CS, Nagasaki T, Tsang SH. Cellular origin of fundus autofluorescence in patients and mice with defective NR2E3 gene. Br J Ophthalmol 2009; Jul 2 (ePub ahead of print)

Gomes NL, Greenstein VC, Carlson JN, Tsang SH, Smith RT, Carr RE, Hood DC, Chang S. A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease. Invest Ophthalmol Vis Sci 2009;50:3953-9. Epub 2009 Mar 25.

Williams GA, Haller JA, Kuppermann BD, Blumenkranz MS, Weinberg DV, Chou C, Whitcup SM; Dexamethasone DDS Phase II Study Group. Dexamethasone posterior-segment drug delivery system in the treatment of macular edema resulting from uveitis or Irvine-Gass syndrome. Am J Ophthalmol 2009;147:1048-54. Epub 2009 Mar 9. 

Gomes NL, Corcostegui I, Fine HF, Chang S. Subfoveal pigment changes in patients with longstanding epiretinal membranes. Am J Ophthalmol 2009;147:865-8. Epub 2009 Feb 20.

Tseng JJ, Schiff WM, Barile GR, Biscette ON, Williams SL, Cekic O, Dhrami-Gavazi E, Chang S. Influence of postoperative lens status on intraocular pressure in proliferative vitreoretinopathy. Am J Ophthalmol. 2009;147:875-85. Epub 2009 Feb 4

Hwang JC, Zernant J, Allikmets R, Barile GR, Chang S, Smith RT. Peripapillary atrophy in Stargardt disease. Retina. 2009;29:181-6.

Donaldson MJ, Bhatnagar P, Dhrami-Gavazi E, Santos RA, Barile GR, Del Priore LV, Iranmanesh R, Schiff WM, Chang S. Pascal dynamic contour tonometry vs. Goldmann applanation tonometry in gas and air-filled eyes after vitrectomy surgery. Retina. 2009;29:481-6.

Song BJ, Cai H, Tsai JC, Chang S, Forbes M, Del Priore LV. Intravitreal recombinant human erythropoietin: a safety study in rabbits. Curr Eye Res. 2008;33:750-60.

Fine HF, Kim E, Flynn TE, Gomes NL, Chang S. Acute posterior multifocal placoid pigment epitheliopathy following varicella vaccine. Br J Ophthalmol. 2008 Aug 26 (Epub ahead of print).

Zhou J, Jang YP, Chang S, Sparrow JR. OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore. Photochem Photobiol. 2008;84:75-80.

Tsui I, Fuchs BS, Chou CL, Chang S, Tsang SH. Non-vascular vision loss in pseudoxanthoma elasticum. Doc Ophthalmol. 2008;117:65-7. Epub 2007 Nov 22.

Hwang J, Escariao P, Iranmanesh R, Tosi GM, Chang S. Outcomes of macular hole surgery in patients treated intraoperatively for retinal breaks and/or lattice degeneration. Retina. 2007;27:1243-8.

Tari SR, Vidne-Hay O, Greenstein VC, Barile GR, Hood DC, Chang S. Functional and structural measurements for the assessment of internal limiting membrane peeling in idiopathic macular pucker. Retina. 2007 Jun;27(5):567-72.

Schiff WM, Hwang JC, Ober MD, Olson JL, Dhrami-Gavazi E, Barile GR, Chang S, Mandava N. Safety and efficacy assessment of chimeric ribozyme to proliferating cell nuclear antigen to prevent recurrence of proliferative vitreoretinopathy. Arch Ophthalmol. 2007;125:1161-7.

Barile G, Chang S, Schiff W. Proliferative vitreoretinopathy. Ophthalmology. 2007;114:1794; author reply 1794-5. No abstract available.

Schiff WM, Barile GR, Hwang JC, Tseng JJ, Cekiç O, Del Priore LV, Chang S. Diabetic vitrectomy: influence of lens status upon anatomic and visual outcomes. Ophthalmology. 2007;114:544-50. Epub 2006 Dec 12.

Ober MD, Barile GR, Tari SR, Tosi GM, Schiff WM, Chang S. Measurement of the actual dose of triamcinolone acetonide delivered by common techniques of intravitreal injection. Am J Ophthalmol. 2006 Oct;142(4):597-600. Erratum in: Am J Ophthalmol. 2007;143:736. Tossi, Gian M [corrected to Tosi, Gian Marco].

Hwang JC, Barile GR, Schiff WM, Ober MD, Smith RT, Del Priore LV, Turano MR, Chang S. Optical coherence tomography in asteroid hyalosis. Retina. 2006;26:661-5.

Chang S. LXII Edward Jackson lecture: open angle glaucoma after vitrectomy. Am J Ophthalmol. 2006;141:1033-1043.

Hwang JC, Chan JW, Chang S, Smith RT. Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2006;47:2655-61.

Pachydaki SI, Tari SR, Lee SE, Ma W, Tseng JJ, Sosunov AA, Cataldergirmen G, Scarmeas N, Caspersen C, Chang S, Schiff WM, Schmidt AM, Barile GR. Upregulation of RAGE and its ligands in proliferative retinal disease. Exp Eye Res. 2006;82:807-15. Epub 2005 Dec 20.

Tosi GM, Schiff W, Barile G, Yoshida N, Chang S. Management of severe hypotony with intravitreal injection of viscoelastic. Am J Ophthalmol. 2005;140:952-4.

Tseng JJ, Barile GR, Schiff WM, Akar Y, Vidne-Hay O, Chang S. Influence of relaxing retinotomy on surgical outcomes in proliferative vitreoretinopathy. Am J Ophthalmol. 2005;140:628-36.

Cekic O, Chang S, Tseng JJ, Barile GR, Del Priore LV, Weissman H, Schiff WM, Ober MD. Intravitreal triamcinolone injection for treatment of macular edema secondary to branch retinal vein occlusion. Retina. 2005;25:851-5.

Cekic O, Chang S, Tseng JJ, Barile GR, Weissman H, Del Priore LV, Schiff WM, Weiss M, Klancnik JM Jr. Intravitreal triamcinolone treatment for macular edema associated with central retinal vein occlusion and hemiretinal vein occlusion. Retina. 2005;25:846-50.

Zhang X, Barile G, Chang S, Hays A, Pachydaki S, Schiff W, Sparrow J. Apoptosis and cell proliferation in proliferative retinal disorders: PCNA, Ki-67, caspase-3, and PARP expression. Curr Eye Res. 2005;30:395-403.

Cekic O, Chang S, Tseng JJ, Akar Y, Barile GR, Schiff WM. Cataract progression after intravitreal triamcinolone injection. Am J Ophthalmol. 2005;139:993-8.

Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, Chang S, Yannuzzi LA, Barile GR, Merriam JC, Smith RT, Olsh AK, Bergeron J, Zernant J, Merriam JE, Gold B, Dean M, Allikmets R. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;17;102:7227-32. Epub 2005 May 3.

Cekic O, Chang S, Schiff WM, Barile GR. Removal of the intruding Miragel scleral buckle by pars plana ultrasonic fragmentation. Am J Ophthalmol. 2005;139:209-10.

Lalin SC, Chang S, Flynn H, Von Fricken M, Del Priore LV. Familial idiopathic macular hole. Am J Ophthalmol. 2004;138:608-11.

Aiello LP, Brucker AJ, Chang S, Cunningham ET Jr, D'Amico DJ, Flynn HW Jr, Grillone LR, Hutcherson S, Liebmann JM, O'Brien TP, Scott IU, Spaide RF, Ta C, Trese MT. Evolving guidelines for intravitreous injections. Retina. 2004;24(Suppl):S3-19.

Tseng JJ, Turano MR Jr, Langton K, Chang S. Measurement of retinal thickness by ocular coherence tomography in a case of scleral transparency in high myopia. Am J Ophthalmol. 2004;138:169-70.

Ciardella AP, Lee GC, Langton K, Sparrow J, Chang S. Autofluorescence as a novel approach to diagnosing macular holes. Am J Ophthalmol. 2004;137:956-9.

Barbazetto IA, Liang J, Chang S, Zheng L, Spector A, Dillon JP. Oxygen tension in the rabbit lens and vitreous before and after vitrectomy. Exp Eye Res. 2004;78:917-24.

Braunstein RE, Airiani S, Chang S. Epithelial ingrowth under a laser in situ keratomileusis flap after phacoemulsification. J Cataract Refract Surg. 2003;29:2239-41.

Ciardella AP, Barile G, Langon K, Chang S: Cytomegalovirus retinitis and FK 506. Am J Ophthalmol 2003;136:386-9.

Ciardella AP, Langton K, Chang S: Intraocular dispersion of perfluorocarbon liquids in silicone oil. Am J Ophthalmol 2003;136:365-7.

Ciardella AP, Schiff W, Barile G, Vidne O, Sparrow J, Langton K, Chang S: Persistent indocyanine green fluorescence after vitrectomy for macular hole. Am J Ophthalmol 2003;136:174-7.

Ciardella AP, Barile G, Schiff W, Del Priore L, Langton K, Chang S: Ruptured retinal arterial macroaneurysm associated with a stage IV macular hole. Am J Ophthalmol 2003;135:907-9.

Barbazetto IA, Lee TC, Rollins IS, Chang S, Abramson DH: Treatment of choroidal melanoma using photodynamic therapy. Am J Ophthalmol 2003;135:898-9.

Charles S, Chang S, McCuen BW: New techniques for hemostasis during diabetic vitrectomy. Retina 2003;23:120-2.

Cekic O, Ohji M, Tano Y, Chang S: Continuous outflow devices for macular translocation with 360-degree retinotomy. Am J Ophthalmol 2003;135:241-3.

Maberley D, Fisher Y, Carvahlo C, Goldbaum M, Raboud J, Shields JA, Chang S, Yannuzzi LA: Variability of three-dimensional ultrasonography for assessment of intraocular tumors. Can J Ophthalmol 2002;37:283-9.

Chang MA, Parides MK, Chang S, Braunstein RE: Outcome of phacoemulsification after pars plana vitrectomy. Ophthalmology 2002;109:948-54.

Ansari H, Rodriguez-Coleman H, Langton K, Chang S; Spontaneous resolution of bilateral stage 1 macular holes documented by optical coherence tomography. Am J Ophthalmol 2002;134:447-449.

Zhang X, Hargitai J, Tammur J, Hutchinson A, Allikmets R, Chang S, Gouras P: Macular pigment and visual acuity on Stargardt macular dystrophy. Graefes Arch Clin Exp Ophthalmol. 2002;240:802-9. Epub 2002 Sep 14.

Doi K, Hargitai J, Kong J, Tsang SH, Wheatley M, Chang S, Goff S, Gouras P: Lentivirus transduction of green fluorescent protein in retinal pigment epithelium: evidence of rejection. Vision Res 2002;42:551-8.

Blumenkranz MS, Ohana E, Shaikh S, Chang S, Coll G, Morse LS, DeBustros S: Adjuvant methods in macular hole surgery: intraoperative plasma-thrombin mixture and postoperative fluid-gas exchange. Ophthalmic Surg Lasers 2001;32:198-207.

Elsing SH, Fekrat S, Green WR, Chang S, Wajer SD, Haller JA: Clinicopathologic findings in eye with retained perfluoro-n-octane liquid. Ophthalmology 2001;108:45-48.

Scott IU, Flynn HW, Lai M, Chang S, Azen SP: First operation anatomic success and other predictors of postoperative vision after complex retinal detachment repair with vitrectomy and silicone oil tamponade. Am J Ophthalmol 2000;130:745-750.

Ohji M, Tano Y, Scheller GD, Chang S: New soft-tipped instruments for foveal translocation surgery with 360 degree retinotomy. Arch Ophthalmol 2000;118:1422-1424.

Schiff WM, Chang S, Mandava N, Barile GR: Pars plana vitrectomy for visually significant vitreous opacities. Retina 2000;20:591-596.

Barile GR, Chang S, Park LS, Reppucci VS, Schiff WM, Schmidt AM: Soluble cellular adhesion molecules in proliferative vitreoretinopathy and proliferative diabetic retinopathy. Curr Eye Res 1999;19:219-227.

Barile GR, Chang S, Horowitz JD, Reppucci VS, Schiff WM, Wong DT: Neovascular complications associated with rubeosis irides in peripheral retinal detachment after retinal detachment surgery. Am J. Ophthalmol. 1998;126:379-389.

Aaberg TM Jr., Rubsamen PE, Flynn HW Jr., Chang S, Mieler WF, Smiddy WE: Giant tear as a complication of attempted removal of intravitreal lens fragments during cataract surgery. Am. J. Ophthalmol. 1997;124:222-226.

Friedlander M, Theesfeld CL, Sugita M, Fruttiger M, Thomas MA, Chang S, Cheresh DA; Involvement of integrins v3 and v5 in ocular neovascular diseases. Proc. Natl. Acad. Sci. (USA) 1996;96: 9764-9769.

Williams RG, Chang S, Comaratta M, Simoni GJ: Does heparin and dexamethsone in the vitrectomy infusate reduce reproliferation in proliferative vitreoretinopathy? Graefes Arch. Clin. Exp. Ophthalmol. 1996;234:496-503.

Coll GE, Sparrow JR, Marinovic A, Chang S: Effect of intravitreal tissue plasminogen activator on experimental subretinal hemorrhage. Retina 1995;15:319-326.

Cohen SM, Flynn HW Jr., Murray TG, Smiddy WE and The Post-vitrectomy Endophthalmitis Study Group: Endophthalmitis after pars plana vitrectomy. Ophthalmology 1995;102:705-712.

Coll G, Chang S, Flynn TE, Brown GC: Communication between the vitreous cavity and the subretinal space in the morning glory syndrome. Graefes Arch. Clin. Exp. Ophthalmol. 1995;233:441-443.

Coll GE, Chang S, Sun J, Wieland MR, Berrocal MH: Perfluorocarbon liquid in the management of retinal detachment with proliferative vitreoretinopathy. Ophthalmology 1995;102:630-638.

Coll GE, Chang S: Surgical techniques for repositioning a dislocated intraocular lens, repair of iridodialysis, and secondary intraocular lens implantation using an innovative 25 gauge forceps. Am. J. Ophthalmol. 1995;119:165-174.

Verstraeten T, Williams GA, Chang S, Cox MS, Trese MT, Moussa M, Friberg T: Lens-sparing vitrectomy with perfluorocarbon liquid for the primary treatment of giant retinal tears. Ophthalmology 1995;102:17-20.

Movshovich A, Berrocal MH, Chang S, Sparrow JR, Simoni GJ: Protective effects of liquid perfluorocarbons during phacofragmentation. Retina 1994;14:457-462.

Stanley Chang, M.D. receives the first international award of the G.B. Bietti Foundation. Retina 1994;14:97.

Stanley Chang, 1992 recipient of the Hermann Wacker Prize of the Club Jules Gonin. Graefes Arch. Clin. Exp. Ophthalmol. 1993;231:675-676.

Goncalves J, Turner L, Chang S: Monitored local anesthesia for pars plana vitrectomy. Ophthalmic Surg. 1993;24:63-64.

Green K, Slagle T, Chaknis MJ, Cheeks L, Chang S: Perfluorocarbon effects on the blood-retinal barrier permeability, Ophthalmic Research 1993;25:186-191.

Sparrow JR, Matthews GP, Iwamoto T, Ross R, Gershbein A, Chang S: Retinal tolerance to perfluoroethylcyclohexane liquid in the rabbit. Retina 1993;13:56-62.

Sparrow JR, Chang S, Vinals AF. Evaluation of the blood-aqueous barrier after vitreous replacement with perfluoropropane gas and liquid silicone. Retina 1992;12:370-375.

Lewis H, Blumenkranz M, Chang S. Treatment of dislocated crystalline lens and retinal detachment with perfluorocarbon liquids. Retina 1992;12:299-304.

Chang S. Multifunction Endolaser Probe (Letter to the Editor), Am. J. Ophthalmol. 1992;114:648.

Sparrow JR, Jayakumar A, Ozmert E, Berrocal M, Chang S. Experimental studies of the com¬bined use of vitreous substitutes of high and low specific gravity. Retina 1992;12:134-140.

Comaratta MR, Chang S, Sparrow JR, Iris. Neovascularization in proliferative vitreoretinopathy. Ophthalmology 1992;99:898-905.

Lopez R, Chang S Long-term results of vitrectomy and perfluorocarbon gas for the treatment of severe proliferative vitreoretinopathy. Am Jnl Ophthalmol 1992;113:424-428.

Lincoff H, Serag Y, Chang S, Silverman R, Bondok B, El-Aswad M. Tractional Elevations of the retina in patients with diabetes. Am Jnl Ophthalmol 1992;113:235-242.

Gordon B, Chang S, Kavanagh M, Berrocal M, Yanuzzi L, Robertson C, Drexler A. The effects of lipid lowering on diabetic retinopathy. Am J of Ophthalmol 1991;112:385-391.

Chang S, Sparrow JR, Iwamoto T, Gershbein A, Ross R, Ortiz R. Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid. Retina 1991;11:367- 374.

Noble KG, Chang S. Adult vitelliform macular degeneration progressing to full- thickness macular hole. Arch Ophthalmol. 1991;109:325.

Sparrow JR, Ortiz R, MacLeish PM, Chang S Fibroblast behavior at aqueous interfaces with perfluorocarbon silicone and fluorosilicone liquids. Invest. Ophthalmol Vis Sci 1990;31:638-646.

Chang S, Reppucci V, Zimmerman NJ, Heinemann MH, Coleman DJ. Perfluorocarbon liquids in the management of traumatic retinal detachments. Ophthalmology 1989;96:785-792.

Chang S, Lincoff H, Zimmerman NJ, Fuchs W. Giant retinal tears: surgical techniques and results using perfluorocarbon liquids. Arch. Ophthalmol. 1989;107:761-766.

Chang S, Ozmert E, Simoni GJ Controlled delivery of perfluorocarbon liquids. Am. Jnl. Ophthalmol. 1989;107:299-300.

Chang S, Ozmert E, Zimmerman NJ Intraoperative perfluorocarbon liquids in the management of proliferative vitreoretinopathy. Am. Jnl. Ophthalmol. 1988;106:668-674.

Coleman DJ, Lucas BC, Fleischman JA, Dennis PH, Chang S, Iwamoto T, Nalbandian RM. A biologic tissue adhesive for vitreoretinal surgery. Retina 1988;8:250-256.

Latanza L, Alfaro DV, Bockman R, Iwamoto T, Heinemann MH, Chang S. Leukotrienes levels in the aqueous humor following experimental ocular trauma. Retina 1988;8:199-204.

Chang S, Lincoff H, Ozmert E, Weinberger D, Maris PJG The management of retinal detachment with moderate proliferative vitreoretinopathy in Freeman HM, Tolentino FI (eds) Proliferative Vitreoretinopathy (PVR), Springer-Verlag, New York, 1988, pp. 54-59.

Coleman DJ, Lucas BC, Rondeau MJ, Chang S. Management of intraocular foreign bodies. Ophthalmology 1987;94:1647-1653.

Lebwohl M, Phelps RG, Yanuzzi LA, Chang S, Schwartz I, Fuchs W. Diagnosis of pseudo¬xanthoma elasticum by scar biopsy in patients without characteristic skin lesions. New England Jnl. Medicine 1987;317:347-350.

Chang S. Low viscosity fluorochemicals in vitreous surgery. Am. Jnl. Ophthalmol. 1987;103:38-43.

Chang S, Zimmerman NJ, Iwamoto T, Ortiz R, Faris D Experimental vitreous replacement with perfluorotributylamine. Am. Jnl. Ophthalmol. 1987;103:29-37.

Burgess SEP, Chang S, Svitra P, Driller J, Lizzi FL, Coleman DJ Effect of hyper¬thermia on experimental choroidal melanoma. Brit. J. Ophthalmol. 1985;69: 854-860.

Chang S, Lincoff H, Coleman DJ, Fuchs W, Farber M Perfluorocarbon gases in vitreous surgery. Ophthalmology 1985;92:651-656.

Coleman DJ, Lizzi FL, Driller J, Rosado AL, Burgess SEP, Torpey JH, Smith ME, Silverman RH, Yablonski ME, Chang S, Rondeau MJ Therapeutic ultrasound in the treatment of glaucoma. II. Clinical applications. Ophthalmology 1985;92:347-353.

Coleman DJ, Lizzi FL, Driller J, Rosado AL, Chang S, Iwamoto T, Rosenthal D Therapeutic ultrasound in the treatment of glaucoma. I. Experimental model. Ophthalmology 1985;92:339-346.

Chang S, Coleman DJ, Lincoff H, Wilcox LM, Braunstein R, Maisel JA Perfluoropropane in proliferative vitreoretinopathy. Am. J. Ophthalmol. 1984;98:180-188.

Chang S, Haik BG, Ellsworth RM, St Louis L, Berrocal JA Treatment of total retinal detachment in the morning glory syndrome. Am. J. Ophthalmol. 1984;97:596-600.

Lizzi FL, Coleman DJ, Driller J, Ostromogilsky M, Chang S, Greenall P Ultrasonic hyperthermia for ophthalmic therapy. IEEE Trans Sonics and Ultrasonics 1984;SU-31, 473- 481.

Lincoff H, Kreissig I, Coleman DJ, Chang S Use of an intraocular gas tamponade to find retinal breaks. Am. Jnl. Ophthalmol. 1983;96:510-516.

Lincoff H, Coleman DJ, Kreissig I, Richard G, Chang S, Wilcox LM The perfluorocarbon gases in the treatment of retinal detachment. Ophthalmology 1983;90:546-551.

Jakobiec FA, Marboe CC, Knowles DM, Iwamoto T, Harrison W, Chang S, Coleman DJ Human sympathetic ophthalmia: an analysis of the inflammatory infiltrate by hybridoma-monoclonal antibodies, immunochemistry and correlative electron microscopy. Ophthalmology 1983;90:76-95.

Blankenship GW, Chang S Diabetic pars plana vitrectomy results and extent of systemic diabetic complications. Acta: XXIV International Congress of Ophthalmology, San Francisco, 1982, JB Lippincott, Philadelphia, 1983.

Peterson CM, Jovanovic LG, Jones RL, Dupuis A, Drexler A, Chang S The role of self blood glucose monitoring and glucose "control" in preventing diabetic sequelae in Friedman EA, L'Esperance FA (eds) Diabetic Renal-Retinal Syndrome vol. 2, Grune & Stratton, New York, 1982.

Chang S, Coleman DJ, Lizzi FL Acoustic measurements of vitreous membrane and retinal thickness in Thijssen JM, Verbeek AM (eds) Docum. Ophthal. Proc. vol.29, Dr. W Junk, The Hague, 1981.

Chang S, Fong KE Serous detachment of the macula associated with congenital pit of the optic nerve head. J. Oph. Photog. 19809;3:58-59.

Abramson DH, Chang S, Coleman DJ Diabetic ketoacidosis with retinal tear. Ann. Ophthalmol. 1977;9:1507-1510.

Abramson DH, Chang S, Coleman DJ Pilocarpine therapy in glaucoma. Effects on anterior chamber depth and lens thickness in patients receiving long-term therapy. Arch. Ophthalmol. 1976;94:914-918.

Abramson DH, Chang S, Coleman DJ, Smith ME Pilocarpine-induced lens changes: an ultrasonic evaluation of dose-response. Arch. Ophthal. 1974;92:464-469.

Book Chapters:

Chang S, Lopez JM Giant tears and proliferative vitreoretinopathy in Ryan S (ed) Retinal Diseases, 3rd edition C.V. Mosby, St. Louis, 2001.

Kwun R, Chang S Perfluorocarbon Liquids in Ryan S (ed) Retinal Diseases, 3rd edition C.V. Mosby, St. Louis, 2001.

Chang S Intraocular gases (revision) in Ryan S (ed) Retinal Diseases, 3rd edition C.V. Mosby, St. Louis, 2001.

Chang S Preoperative assessment of the retinal detachment patient in Packer AJ (ed) Manual of Retinal Surgery, 2nd edition, Butterworth-Heinemann, Boston, 2001.

Chang S, Lopez JM Vitreous Surgery in Regillo C, Smiddy WM, Flynn H (eds) Vitreoretinal Disease – The Essentials, Thieme, New York, 1999

Sparrow JR, Chang S Adjuncts to vitreous surgery in Albert DM (ed): Ophthalmic Surgery: Principles and Techniques. Blackwell Science, Malden, 1999.

Schiff W, Chang S, Reppucci VS, Wong DT Surgical management of giant retinal tears in Guyer DR, Yannuzzi LA, Chang S, Shields JA, Green WR (editors): Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999.

Chang S, Sparrow JR Vitreous substitutes in Guyer DR, Yannuzzi LA, Chang S, Shields JA, Green WR (editors): Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999.

Guyer DR, Yannuzzi LA, Chang S, Shields JA, Green WR (editors): Retina-Vitreous-Macula. W.B. Saunders, Philadelphia, 1999.

Chang S Vitrectomy in Duker J, and Yanoff MA (eds) Ophthalmology. Mosby, London, 1999.

Chang S. Giant retinal tears: Surgical management with perfluorocarbon liquids in Lewis H and Ryan SJ (eds) Medical and Surgical Retina: Advances, Controversies and Management. C.V. Mosby, St Louis, 1993.

Sparrow JR, Chang, S Vitreous substitutes in Albert DM, Jakobiec FA (eds) Principles and Practice of Ophthalmology, Williams and Wilkins, Philadelphia, 1993.

Chang S, Ozmert E, Zimmerman NJ Intraoperative perfluorocarbons in the manage¬ment of severe proliferative vitreoretinopathy in Heimann K, Weidemann P (eds) Proliferative Vitreoretinopathy, Kaden Verlag, Heidelberg, 1989.

Chang S Preoperative evaluation of the retinal detachment patient in Packer AJ (ed), Manual of Retinal Surgery, Churchill-Livingston, New York, 1989

Chang S, Lincoff H, et al Management of Retinal Detachment with Moderate PVR in Freeman HM, Tolentino FI (eds) Proliferative Vitreoretinopathy (PVR), Springer Verlag, New York, Inc., New York, 1988.

Chang S Intraocular gases in Ryan S, Glaser BM, Michels RG (eds) Retinal Diseases, C.V. Mosby, St. Louis, 1988, Vol 3. pp. 245-259.

Chang S, Coleman DJ, Lizzi FL Therapeutic Ultrasound in Ophthalmology in Tso, MOM (ed) Retinal Diseases: Biomedical Foundations and Clinical Management, J.B. Lippincott, Philadelphia 1987.

Chang S, Coleman DJ Ultrasonography of Vitreoretinal Diseases in Tso, MOM (ed) Retinal Diseases: Biomedical Foundations and Clinical Management, J.B. Lippincott, Philadelphia 1987.

Jovanovic L, Chang S, Peterson CM Medical management of the diabetic patient with retinopathy in Jakobiec FA, Sigelman J (eds.) Advanced Techniques in Ocular Surgery, W.B. Saunders, Philadelphia 1984.

Chang S, Smith ME, Coleman DJ Emergency ophthalmic ultrasound in Taylor K, Viscomi G (eds) Clinics in Diagnostic Radiology: Diagnostic Ultrasound in Emergency Medicine, Churchill-Livingstone, New York, 1981.

Chang S, Coleman DJ, Smith ME Ultrasonography of pediatric ocular tumors in Nicholson DH, Green WR (eds) Pediatric Ocular Tumors, Masson, New York, 1981.

Chang S, Dallow RL, Coleman DJ Ultrasound diagnosis of intraocular tumors in Jakobiec FA (ed) Ocular and Adnexal Tumors, Aescalapius, Birmingham, 1978.

Reviews:

Fine HF, Biscette O, Chang S, Schiff WM. Ocular hypotony: a review. Compr Ophthalmol Update. 2007; 8(1):29-37.

Chang S Perfluorocarbon liquids in vitreoretinal surgery. Int. Ophthalmol. Clinics 32:153-164, 1992.

Comaratta MR, Chang S Perfluorocarbon liquids in the management of complicated retinal detachments. Current Opinion in Ophthalmol. 2:291-298, 1991.

Chang S, Coleman DJ, Smith ME Ophthalmic ultrasonography in Sanders RC, Hill M (eds) Ultrasound Annual, Raven Press, New York, 1983.

Coleman DJ, Lizzi FL, Chang S, Driller J Applications of therapeutic ultrasound in ophthalmology in Kurjak A (ed) Progress in Medical Ultrasound: Reviews and Comments Vol. 2, Excerpta Medica, Amsterdam, 1981.

Chang S, Coleman DJ, Dallow RL Trends in ophthalmic ultrasound in Kurjak A (ed) Progress in Medical Ultrasound: Reviews and Comments vol. 1, Excerpta Medica, Amsterdam, 1980.

Locations

Edward S. Harkness Eye Institute

635 West 165th Street
Suite Flanzer
New York, NY 10032

Phone: (212) 305-9535

Fax: (212) 342-5293

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880 Third Avenue
New York, NY 10022

Phone: (212) 305-9535

Fax: (212) 201-4129

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K.K. Tse and Ku Teh Ying Professor of Ophthalmology

2012 Guillermo Pico Lecture, Puerto Rican Ophthalmology Society, San Juan, PR

2011 Visionary Award, Foundation Fighting Blindness, New York, NY

2011 Optic UK lecture, Royal College of Ophthalmologists, Birminghan, England

2011 Charles L. Schepens MD lecture, American Academy of Ophthalmology, Orlando, FL

2010 Mark Schoenberg Lecture, New York Clinical Society for Ophthalmology, New York, NY

2010 Guest of Honor, Retina Society annual meeting, San Francisco, CA

2010 Silver Fellow, Association for Research in Vision and Ophthalmology

2009 Honorary Member, Brazilian Retinal Society

2009 Gianbattista Bietti International Medal, Italian Society of Ophthalmology, Rome, Italy

2009 Lifetime Achievement Award, American Academy of Ophthalmology, San Francisco, CA

2008 Stuart Brown Lecture, Dept. of Ophthalmology, University of California at San Diego, San Diego, CA

2008 National Physician of the Year, Castle-Connolly Guides, New York, NY

2008 Honorary Member, Spanish Retinal Society, Zaragosa, Spain

2008 Invited Honorary Speaker, British and Irish Vitreoretinal Surgery Society, London, England

2008 Crystal Apple Award, American Society of Retinal Specialists, Maui, Hawaii

2007 Victor Curtin Visiting Professor, Dept. of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL

2006 Hobie Award, New York State Ophthalmology Society, New York, NY

2005 Kambara Distinguished Visiting Professor, Dept. of Ophthalmology, University of Tennessee – Memphis, Memphis, TN

2005 Invited guest lecturer, Moorfields Eye Hospital Bicentennial, London, England

2005 Sean Murphy Lecture, Dept. of Ophthalmology, McGill University, Montreal, Canada

2005 Ingrid Kreissig Lecture, Euretina, Barcelona, Spain

2005 LXII Edward Jackson Lecture, American Academy of Ophthalmology, Las Vegas, NV

2004 Irving Leopold Lecture, Dept. of Ophthalmology, Mount Sinai School of Medicine, New York, NY

2004 Lois A. Young Lecture, Dept. of Ophthalmology, Howard University, Washington, DC

2003 Claes H. Dohlman Lecture, Mass. Eye & Ear Infirmary, Harvard Medical School, Boston, MA.

2003 Jules Stein Lecture, Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles, CA.

2003 Curts Visiting Professor, Dept. of Ophthalmology, Dartmouth School of Medicine, Hanover, NH

2002 Roscoe Kennedy Lecture, Cleveland Clinic Foundation, Cleveland, OH.

2002 Edward W.D. Norton Lecture, University of Miami, Miami, FL.

2001 D. Jackson Coleman Lecture, Weill-Cornell Medical College, New York, NY.

2001 Phillip T. Ellis Lecture, University of Colorado, Denver, CO.

2000 Everett Goar Lecture, Houston Ophthalmological Society, Houston, TX.

2000 Harold Gifford Lecture, University of Nebraska, Omaha, NE.

2000 Award, Conselho Brasiliero de Oftalmologia, Sao Paulo, Brazil

1999 Alcon Research Institute Award

1999 Scientific Achievement Award, Chinese American Medical Society, New York, NY.

1998 Senior Honor Award, American Academy of Ophthalmology

1998 Taylor R. Smith Lecture, Aspen Retinal Detachment Society, Aspen, CO.

1998 W.H. Helmerich III Award, Vitreous Society

1998 A. Gerard DeVoe Lecture, Columbia University, New York, NY.

1997 G. Victor Simpson Lecture, Washington Hospitals Center, Washington D.C.

1997 Arthur J. Bedell Lecture, Wills Eye Hospital, Philadelphia, PA.

1995 Listed, America’s Best Doctors, America’s Health Magazine

1994 Delmar Nachazel Lecture, Beaumont Hospital, Royal Oak, MI.

1993 John Milton McLean Medal, Cornell University Medical College, New York, N.Y.

1993 A. Raymond Pilkerton Lecture, Georgetown University, Washington, D.C.

1993 Ronald G. Michels Lecture, The Retina Institute of Maryland, Baltimore, Maryland.

1993 First G.B. Bietti International Foundation Award, Rome, Italy. Awarded for outstanding contributions to retinal research.

1993 Keynote Address, Sankara Nethralaya Alumni Association, Bombay, India.

1993 Scientific Achievement Award, Escalon, Inc., New Brunswick, N.J.

1992 Hermann Wacker Prize, Vienna, Austria. Awarded biennially by the Club Jules Gonin, an international retinal society, for the most innovative contributions to vitreoretinal disease

1992 Harvey B. Taterka Memorial Lecture, New York University School of Medicine, New York, NY

1991 Listed, Best Doctors in America

1991 Listed, The Best Doctors in New York, New York Magazine

1991 David and Mary Seslen Lecture, Washington University Medical Center, St. Louis, MO.

1989 Listed, Directory of Outstanding Medical Specialists in the U.S., Town and Country Magazine

1988 Honor Award, American Academy of Ophthalmology

1987 Service Certificate, American Academy of Ophthalmology

1974 Alvin M. Behrens Award for Ophthalmology, Columbia Univ.

1974 Alpha Omega Alpha, Columbia University

1968-1970 Ford Foundation Fellowship, University of Pennsylvania

2000-2012 America’s Top Doctors, Castle-Connolly Guide

1996-2012 Listed, The Best Doctors in New York, New York Magazine

1995-2012 Listed, Best Doctors in America