The physicians in the Metabolic Bone Disease and Osteoporosis Service at Weill Cornell Orthopedics at NewYork-Presbyterian/Weill Cornell Medical Center treat diseases that lead to bone fragility.
The diagnosis of these bone conditions may include a bone density scan — a safe, painless x-ray technique that compares your bone density to the peak bone density that someone of your same gender and ethnicity should have reached at 20 to 25 years of age.
Our physicians may also order blood and urine tests to look for markers — levels of different enzymes, proteins, and other substances circulating in the body that give information about your disease and the progress of your treatment. These markers can provide information about the rate of bone formation, bone resorption (loss of bone), and vitamin D levels, which are essential for the body’s absorption of calcium.
In addition, our physicians may also perform genetic evaluations for patients suspected of having a genetic disease associated with fractures.
There are many drug treatments for osteoporosis. These include bisphosphonate drugs such as Fosamax (alendronate), Actonel (risedronate), and the monthly drug Boniva (ibandronate). These drugs help slow or stop bone loss. Another treatment option is Forteo (teriparatide), an injectable synthetic version of parathyroid hormone, a naturally occurring hormone that helps regulate calcium. This treatment helps build new bone.
There are a number of surgical treatments for fragility fractures. We perform many of these techniques percutaneously (through the skin) using minimally invasive micro-techniques. These include:
For patients with delayed fracture healing, we offer treatment including percutaneous injections of concentrated marrow cells, along with demineralized bone matrix (a bone-graft substitute) or bone morphogenetic protein (which stimulates the body to make more bone cells), and systemic treatment with parathyroid PTH (1-34), which has been shown to increase bone density and prevent fractures in both postmenopausal women and patients on corticosteroids.
We also heal fractures using a person's own bone marrow that has been concentrated, along with demineralized bone.
We offer a comprehensive program for treating avascular necrosis – the death of bone tissue due to a lack of blood supply. This can lead to tiny breaks in the bone and the bone's eventual collapse. Avascular necrosis most often affects the head of the thighbone (femur), but it may also affect other bones. Treatment includes:
At Weill Cornell Orthopedics, areas of research include methods to image the structure of bones and the molecular activity taking place within them. These include:
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