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Leading hematologists from NewYork-Presbyterian Hospital and Columbia University Medical Center are presenting new basic and clinical research findings at the 46th annual American Society of Hematology (ASH) meeting in Atlanta, Dec. 8-11.

Highlights from the symposium presentations and posters to be made by NewYork-Presbyterian/Columbia physician-scientists include the following presenters/presentations:

Dr. Riccardo Dalla-Favera—Percy and Joanne Uris Professor of Pathology, professor of genetics and development; director of the Institute for Cancer Genetics; director of the Herbert Irving Comprehensive Cancer Center.

• Investigating Mature B-Cell Lymphomas by MicroRNA Profiling, by Drs. Katia Basso, Andrea Califano, Riccardo Dalla-Favera, Yukiko Kitagawa, Pavel Morozov, et al. Poster Session: Disordered Gene Expression in Hematologic Malignancy. Monday, Dec. 10, 5:00 p.m.

Dr. Carlos Cordon-Cardo—professor and vice chair of the Department of Pathology and professor, Department of Urology, associate director of the Herbert Irving Comprehensive Cancer Center.

• Inhibition of NOTCH1 Signaling Reverses Glucocorticoid Resistance in T-ALL, by Drs. Mireia Castillo, Carlos Cordon-Cardo, Adolfo Ferrando, Teresa Palomero, Valeria Tosello, et al. Simultaneous Session: Acute Lymphocytic Leukemia: Biology and Pathophysiology I. Monday, Dec. 10, 7:30 a.m.

Dr. Ramon Parsons—Avon Foundation Professor of Breast Cancer Research, Departments of Pathology and Medicine, Institute for Cancer Genetics, and Herbert Irving Comprehensive Cancer Center.

• Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-ALL, by Drs. Govind Bhagat, Adolfo Ferrando, Teresa Palomero, Ramon Parsons, et al. Plenary Scientific Session. Sunday, Dec. 9, 1:30 p.m.

Dr. Owen O'Connor—associate professor of medicine, chief of the lymphoma service, director of the Lymphoid and Malignancy Program, Herbert Irving Comprehensive Cancer Center.

• Safety and Antitumor Efficacy of the Proteasome Inhibitor Carfilzomib (PR-171) Dosed for Five Consecutive Days in Hematologic Malignancies: Phase 1 Results, by Owen A. O'Connor, et al. Simultaneous Session: Myeloma: Novel Therapies in Relapsed Multiple Myeloma. Monday, Dec. 10, 11:00 a.m.

NewYork-Presbyterian Hospital

NewYork-Presbyterian Hospital—based in New York City—is the nation's largest not-for-profit, non-sectarian hospital, with 2,242 beds. It provides state-of-the-art inpatient, ambulatory and preventive care in all areas of medicine at five major centers: NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian Hospital/Columbia University Medical Center, Morgan Stanley Children's Hospital of NewYork-Presbyterian, NewYork-Presbyterian Hospital/Allen Pavilion and NewYork-Presbyterian Hospital/Westchester Division. One of the largest and most comprehensive health-care institutions in the world, the Hospital is committed to excellence in patient care, research, education and community service. It ranks sixth in U.S.News & World Report's guide to "America's Best Hospitals," ranks first on New York magazine's "Best Hospitals" survey, has the greatest number of physicians listed in New York magazine's "Best Doctors" issue, and is included among Solucient's top 15 major teaching hospitals. The Hospital is ranked with among the lowest mortality rates for heart attack and heart failure in the country, according to a 2007 U.S. Department of Health and Human Services (HHS) report card. The Hospital has academic affiliations with two of the nation's leading medical colleges: Weill Cornell Medical College and Columbia University College of Physicians and Surgeons.

Columbia University Medical Center

Columbia University Medical Center provides international leadership in pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders and includes the dedicated work of many physicians, public health professionals, dentists, nurses, and scientists at the College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. For more information, visit www.cumc.columbia.edu.