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Interventional Cardiologist Joins Komansky Center for Children's Health

New York (Jan 28, 2010)

The Komansky Center for Children's Health at New York-Presbyterian Hospital/Weill Cornell Medical Center is pleased to welcome Ajay J. Mirani, MD, as Site Director of Pediatric Interventional Cardiology. Dr. Mirani, Assistant Professor of Pediatrics in the Department of Pediatric Cardiology at Weill Cornell Medical College and Columbia University College of Physicians and Surgeons, is also a member of the joint Pediatric Interventional Cardiology team at New York-Presbyterian Morgan Stanley Children's Hospital.

Dr. Mirani most recently served on the medical faculty at the Robert Wood Johnson Medical School as Clinical Instructor of Pediatrics, where he was actively involved in patient care and in medical education. Simultaneously, he worked as a Pediatric Emergency Department physician at Robert Wood Johnson University Hospital.

Dr. Mirani completed his undergraduate studies at Johns Hopkins University, his Master of Science degree at the University of Pittsburgh, and his Doctor of Medicine at Temple University School of Medicine. He completed his internship and residency training in pediatrics at the University of Medicine and Dentistry of New Jersey - Robert Wood Johnson Medical School. Dr. Mirani then went on to complete fellowship training in Pediatric Cardiology and Interventional Pediatric Cardiology (cardiac catheterization) in the joint fellowship program at New York-Presbyterian Hospital.

"I've always had a love for physiology and for physics in general," says Dr. Mirani, "and the perfect combination of these fields I found in cardiology. These interests along with my passion to advocate for the health and well being of children naturally led me to pursue a career in pediatrics and pediatric cardiology."

Treating Congenital Heart Disease

Dr. Mirani is skilled in performing diagnostic and interventional cardiac catheterizations on patients of all ages with congenital heart disease, including:

  • catheter based closure of atrial septal defects
  • device closure of a patent ductus arteriosus
  • balloon valvuloplasty for aortic valve stenosis and pulmonary valve stenosis
  • cardiac biopsies for heart transplant patients
  • balloon angioplasty, and
  • stent placement for coarctation of the aorta and for pulmonary artery stenosis.

Dr. Mirani is also trained in performing diagnostic and interventional cardiac catheterizations for patients with heart conditions, including:

  • dilated or restrictive cardiomyopathy
  • ventricular septal defects
  • Tetralogy of Fallot
  • hypoplastic left heart syndrome
  • tricuspid atresia
  • Ebstein's anomaly
  • truncus arteriosus, and
  • transposition of the great arteries

"Most of our patients have congenital heart disease with severely malformed hearts, and some patients have minor defects," says Dr. Mirani. "Catheterization procedures can diagnose and treat a whole spectrum of disorders, ranging from closing a small hole in the heart to managing a patient in whom a large part of the heart that has not even developed. What makes our service unique and innovative are the types of procedures that we're able to do now via catheterization. The patient's cardiac defect may no longer require having a large incision or open-heart surgery to repair it."

Interventional Cardiology—A Rapidly Changing Field

Interventional cardiology has undergone tremendous expansion and change over the past 20 years, with the introduction of many new techniques and devices. Balloon valvuloplasty has become the treatment of choice for pulmonary valve stenosis at all ages and is also the treatment of choice for aortic valve stenosis in neonates, children, and young adults.

"In recent years, there have been many iterations and changes in interventional procedures, as well as with surgical approaches," says Dr. Mirani. "As a result, patients are starting to survive much, much longer. Patients who would not previously have lived more than a few hours after birth are now able to undergo an emergent, interventional cardiology procedure as well as surgery within the newborn period. It's very gratifying to see newborn infants recover, go home with their parents, and go on to lead normal lives."

Some young patients are able to wait longer and may eventually have interventional procedures within the first few years of life. "With certain heart defects, we are able to wait until the child is a little bit older, usually within the school-age range," says Dr. Mirani. "This is because as the heart gets bigger, we have more room in which to work, thereby further reducing the risk of complications."

Research Interests

Dr. Mirani's research interests focus on novel catheter based techniques, and he is a member of the pediatric cardiac catheterization team studying investigational devices new to the United States including:

  • COAST (Coarctation of the Aorta Stent Trial)
  • Melody® Valve (Trans-catheter based pulmonary valve stent)
  • AMPLATZER® Duct Occluder II (ADO II) for a patent ductus arteriosus

For More Information

The Pediatric Interventional Cardiology program at the Komansky Center for Children's Health is available for urgent and emergent services 24/7. For more information, please call (212) 746-3561.

Faculty Contributing to this Article:
Ajay J. Mirani, MD, Site Director of Pediatric Interventional Cardiology, Komansky Center for Children's Health at New York-Presbyterian Hospital/Weill Cornell Medical Center, and Assistant Professor of Pediatrics in the Department of Pediatric Cardiology at Weill Cornell Medical College and Columbia University College of Physicians and Surgeons

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